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| 카탈로그 번호 | HA021013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | ELISA | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | SAA1910 | ||||
| 타겟 | Von Ebner protein Hl, SPLUNC1, Palate lung and nasal epithelium clone protein, PLUNC, SPURT, Lung-specific protein X, Tracheal epithelium-enriched protein, BPI fold-containing family A member 1, BPIFA1, Secretory protein in upper respiratory tracts, Nasopharyngeal carcinoma-related protein, LUNX, Short PLUNC1, NASG | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | Q9NP55 | ||||
| RRID | Anti-Human BPIFA1/LunX Antibody (SAA1910) (abinScience Cat# HA021013, RRID:AB_3727674) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | BPI fold-containing family A member 1 (BPIFA1/LunX) is a ~26 kDa protein. Lipid-binding protein which shows high specificity for the surfactant phospholipid dipalmitoylphosphatidylcholine (DPPC). Plays a role in the innate immune responses of the upper airways. Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae. Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus. Plays a role in the airway inflammatory response after exposure to irritants. 1. Ning, F. et al. (2014) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 28, 5349-60. PMID: 25223608 2. Sayeed, S. et al. (2013) Infection and immunity 81, 285-91. PMID: 23132494 3. Liu, Y. et al. (2013) The American journal of pathology 182, 1519-31. PMID: 23499554 4. Walton, WG. et al. (2016) Biochemistry 55, 2979-91. PMID: 27145151 5. Garland, AL. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 15973-8. PMID: 24043776 6. Hobbs, CA. et al. (2013) American journal of physiology. Lung cellular and molecular physiology 305, L990-L1001. PMID: 24124190 7. Lindahl, M. et al. (2001) Electrophoresis 22, 1795-800. PMID: 11425234 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human BPIFA1/LunX Antibody (SAA1910)
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