

| 카탈로그 번호 | HT375013 | ||||
|---|---|---|---|---|---|
| 설명 |
Anti-Human BUB1B Recombinant Antibody (SAA1518) (HT375013) is a mouse monoclonal antibody detecting BUB1B in ELISA. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||
| 응용 분야 | ELISA | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | SAA1518 | ||||
| 타겟 | SSK1, MAD3/BUB1-related protein kinase, BUB1B, Mitotic checkpoint serine/threonine-protein kinase BUB1 beta, BUBR1, MAD3L, Protein SSK1, hBUBR1, Mitotic checkpoint kinase MAD3L | ||||
| 내독소 수준 | < 10 EU/mg as determined by LAL method. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | O60566 | ||||
| RRID | Anti-Human BUB1B Antibody (SAA1518) (abinScience Cat# HT375013, RRID:AB_3727279) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (BUB1B) is a ~119 kDa protein. Essential component of the mitotic checkpoint. Required for normal mitosis progression. The mitotic checkpoint delays anaphase until all chromosomes are properly attached to the mitotic spindle. One of its checkpoint functions is to inhibit the activity of the anaphase-promoting complex/cyclosome (APC/C) by blocking the binding of CDC20 to APC/C, independently of its kinase activity. The other is to monitor kinetochore activities that depend on the kinetochore motor CENPE. | ||||
| 참고사항 | For research use only. | ||||
| Isotype Control | Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023) |

SDS-PAGE for Anti-Human BUB1B Antibody (SAA1518).


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