Anti-Human C1S Recombinant Antibody (SAA0510), PE (HY598127)

Name: Anti-Human C1S Recombinant Antibody (SAA0510), PE
Brand: abinScience
SKU: HY598127
Price: 290 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD):

사양:

50T
100T

수량:

문의하기

개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호	HY598127
종 반응성	Human
응용 분야	ELISA, FCM, WB
숙주 종	Mouse
클론성	Monoclonal
이소타입	IgG2a, kappa
클론 ID	SAA0510
접합	PE
타겟	C1 esterase, Complement C1s subcomponent, C1S, Complement component 1 subcomponent s
내독소 수준	Please contact with the lab for this information.
관련 제품	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), PE
등록번호	P09871
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Store at 4°C for 12 months. Protect from light. Do not freeze.
배경	Complement C1s subcomponent is a ~76 kDa protein. Component of the complement C1 complex, a multiprotein complex that initiates the classical pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. C1S is activated following association of the C1 complex with immunoglobulins (IgG or IgM) complexed with antigens to form antigen-antibody complexes on the surface of pathogens. C1S is cleaved and activated by C1R to generate C1s subcomponent heavy and light chains. C1s subcomponent light chain then cleaves and activates C2 and C4, the next components of the classical complement pathway. 1. Lacroix, M. et al. (2001) The Journal of biological chemistry 276, 36233-40. PMID: 11445589 2. Kerr, FK. et al. (2005) The Journal of biological chemistry 280, 39510-4. PMID: 16169853 3. Kerr, MA. et al. (1978) The Biochemical journal 171, 99-107. PMID: 417728 4. Reboul, A. et al. (1979) FEBS letters 103, 156-61. PMID: 467643 5. McRae, BJ. et al. (1981) The Journal of biological chemistry 256, 12362-6. PMID: 6271784 6. Thielens, NM. et al. (1982) FEBS letters 141, 19-24. PMID: 6282646 7. Thielens, NM. et al. (1984) FEBS letters 165, 111-6. PMID: 6319179 8. Nagasawa, S. et al. (1977) Proceedings of the National Academy of Sciences of the United States of America 74, 2998-3001. PMID: 70787 9. Rossi, V. et al. (1998) The Journal of biological chemistry 273, 1232-9. PMID: 9422791 10. Zwarthoff, SA. et al. (2021) Proceedings of the National Academy of Sciences of the United States of America 118. PMID: 34155115
참고사항	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.