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| 카탈로그 번호 | HP586014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human CALHM6 (Arg197-Ile309). | ||||||||
| 타겟 | C6orf187, FAM26F, Calcium homeostasis modulator protein 6, Protein FAM26F, CALHM6 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q5R3K3 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Calcium homeostasis modulator protein 6 (CALHM6) is a ~34 kDa protein. Pore-forming subunit of an ATP-permeable channel. In response to pathogen-derived and proinflammatory stimuli, relocates from intracellular compartments to NK-dendritic cell and NK-macrophage immune synapses where it mediates ATP efflux and NK cell activation involved in antimicrobial and antitumor responses. May assemble to form gap junction channel-like structures with gating and ion conductance likely regulated by membrane lipids and voltage rather than by extracellular calcium levels. 1. Drożdżyk, K. et al. (2020) eLife 9. PMID: 32374262 | ||||||||
| 참고사항 | For research use only. |
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