中文
English
한국어
日本語
Español
Français
Русский
| 카탈로그 번호 | HX155107 |
|---|---|
| 종 반응성 | Human |
| 응용 분야 | ELISA, FCM, WB |
| 숙주 종 | Mouse |
| 클론성 | Monoclonal |
| 이소타입 | IgG2a, kappa |
| 클론 ID | SAA0539 |
| 타겟 | C-C motif chemokine 7, MCP-3, CCL7, Monocyte chemotactic protein 3, Monocyte chemoattractant protein 3, NC28, Small-inducible cytokine A7, SCYA6, SCYA7, MCP3 |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >95% as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P80098 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS, pH 7.4, 0.09% Sodium azide. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 배경 | C-C motif chemokine 7 (CCL7/MCP-3) is a ~11 kDa protein. Chemotactic factor that plays an important role in immune regulation. Attracts monocytes, eosinophils, basophils, and T-cells to sites of inflammation or infection. Upon binding to various chemokine receptors including CCR1, CCR2, CCR3, and CCR5, facilitates immune cell migration by guiding them to infected tissues. Interacts with CCR2 to facilitate the release of monocytes from the bone marrow into the bloodstream, maintaining monocyte homeostasis. In turn, monocytes recruited to inflamed or injured tissues can differentiate into macrophages or dendritic cells, which are essential for immune defense and tissue repair. 1. Bonini, JA. et al. (1997) DNA and cell biology 16, 1249-56. PMID: 9364936 2. Blanpain, C. et al. (1999) Blood 94, 1899-905. PMID: 10477718 3. Wei, H. et al. (2024) Cellular signalling 117, 111122. PMID: 38417634 |
| 참고사항 | For research use only. |
Flow-cytometry using anti-human CCL7 antibody.LPS treated THP-1 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CCL7 antibody monoclonal antibody (Catalog # HX155107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.
Western blot analysis was performed using anti-CCL24/Eotaxin-2/MPIF-2 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CCL24/Eotaxin-2/MPIF-2 (Catalog No: HT048012)
Lane 2: negative control
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
