Anti-Human CD11b/ITGAM Recombinant Antibody (mAb107), PerCP (HY474147)

Name: Anti-Human CD11b/ITGAM Recombinant Antibody (mAb107), PerCP
Brand: abinScience
SKU: HY474147
Price: 142 USD
Availability: InStock

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개요

카탈로그 번호	HY474147
종 반응성	Human
응용 분야	DB, FCM
숙주 종	Mouse
클론성	Monoclonal
이소타입	IgG1, kappa
클론 ID	mAb107
접합	PerCP
타겟	CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, ITGAM, CD11b, CD11 antigen-like family member B, Integrin alpha-M, CR3A, CD11B, Neutrophil adherence receptor
내독소 수준	Please contact with the lab for this information.
관련 제품	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), PerCP
등록번호	P11215
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Store at 4°C for 12 months. Protect from light. Do not freeze.
배경	Integrin alpha-M (CD11b/ITGAM) is a ~127 kDa protein. Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen and factor X. It recognizes P1 and P2 peptides of fibrinogen gamma chain. 1. Losse, J. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 184, 912-21. PMID: 20008295 2. DiScipio, RG. et al. (1998) Journal of immunology (Baltimore, Md. : 1950) 160, 4057-66. PMID: 9558116 3. Bai, M. et al. (2017) Blood 130, 2092-2100. PMID: 28807980 4. Jerke, U. et al. (2011) The Journal of biological chemistry 286, 7070-81. PMID: 21193407 5. Diamond, MS. et al. (1990) The Journal of cell biology 111, 3129-39. PMID: 1980124
참고사항	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human CD11b/ITGAM Recombinant Antibody (mAb107), PerCP.pdf

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Anti-Human CD11b/ITGAM Recombinant Antibody (mAb107), PerCP (HY474147)

개요

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