Anti-Human TNF RII/TNFRSF1B Recombinant Antibody (E4#), PerCP (HB070147)

Name: Anti-Human TNF RII/TNFRSF1B Recombinant Antibody (E4#), PerCP
Brand: abinScience
SKU: HB070147
Price: 268 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD):

사양:

50T
100T

수량:

문의하기

개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호	HB070147
종 반응성	Human
응용 분야	ELISA, FCM
숙주 종	Mouse
클론성	Monoclonal
이소타입	IgG1, kappa
클론 ID	E4#
접합	PerCP
타겟	TNF-R2, TNFR-II, p80 TNF-alpha receptor, Etanercept, TNFBR, TBP-2, TBPII, Tumor necrosis factor receptor superfamily member 1B, CD120b, p75, TNFRSF1B, Tumor necrosis factor receptor 2, TNF-RII, TNFR2, Tumor necrosis factor receptor type II
내독소 수준	Please contact with the lab for this information.
관련 제품	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), PerCP
등록번호	P20333
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Store at 4°C for 12 months. Protect from light. Do not freeze.
배경	Tumor necrosis factor receptor superfamily member 1B (CD120b/TNFR2) is a ~48 kDa protein. Receptor with high affinity for TNFSF2/TNF and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF. Isoform 2 blocks TNF-induced apoptosis, which suggests that it regulates TNF function by antagonizing its biological activity.
참고 문헌	1. Goffe B, et al. Etanercept: An overview. J Am Acad Dermatol. 2003;49(2 Suppl):S105-S111. [HB070147] 2. Goldenberg MM. Etanercept, a novel drug for the treatment of patients with severe, active rheumatoid arthritis. Clin Ther. 1999;21(1):75-2. [HB070147] 3. Haraoui B, et al. Etanercept in the treatment of rheumatoid arthritis. Ther Clin Risk Manag. 2007;3(1):99-105. [HB070147] 4. Totoson P, et al. Etanercept improves endothelial function via pleiotropic effects in rat adjuvant-induced arthritis. Rheumatology (Oxford). 2016;55(7):1308-1317. View More [HB070147]
참고사항	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.