Anti-Human ALCAM/CD166 Polyclonal Antibody (HC678014)

Name: Anti-Human ALCAM/CD166 Polyclonal Antibody
Brand: abinScience
SKU: HC678014
Price: 168 USD
Availability: InStock

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50ug
100ug

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HC678014

설명

Anti-Human CD166/ALCAM Polyclonal Antibody (HC678014) is a rabbit polyclonal antibody detecting ALCAM. Suitable for Human, Mouse, and Rat.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human CD166/ALCAM (Trp28-Lys527).

타겟

ALCAM, Activated leukocyte cell adhesion molecule, CD166, CD166 antigen, MEMD

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

Q13740

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

CD166 antigen (ALCAM) is a ~65 kDa protein. Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts. Promotes T-cell activation and proliferation via its interactions with CD6. Contributes to the formation and maturation of the immunological synapse via its interactions with CD6. Mediates homotypic interactions with cells that express ALCAM. Acts as a ligand for the LILRB4 receptor, enhancing LILRB4-mediated inhibition of T cell proliferation.

1. Hassan, NJ. et al. (2004) European journal of immunology 34, 930-40. PMID: 15048703

2. Ikeda, K. et al. (2004) The Journal of biological chemistry 279, 55315-23. PMID: 15496415

3. Zimmerman, AW. et al. (2006) Blood 107, 3212-20. PMID: 16352806

4. Iolyeva, M. et al. (2013) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 27, 978-90. PMID: 23169771

5. Escoda-Ferran, C. et al. (2014) FEBS letters 588, 2805-13. PMID: 24945728

6. Bowen, MA. et al. (1995) The Journal of experimental medicine 181, 2213-20. PMID: 7760007

7. Gimferrer, I. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 2262-70. PMID: 15294938

8. Xu, Z. et al. (2018) Journal of immunology (Baltimore, Md. : 1950) 200, 1207-1219. PMID: 29263213

9. Chitteti, BR. et al. (2014) Blood 124, 519-29. PMID: 24740813

참고사항

For research use only

이미지

Western blot

Western blot analysis was performed using anti-ALCAM polyclonal antibody at 1ug/mL on various samples.
Lane 1: Hela cell lysate
Lane 2: U2OS cell lysate

참고 문헌

데이터시트

Anti-Human ALCAM/CD166 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human ALCAM/CD166 Polyclonal Antibody (HC678014)

개요

이미지

참고 문헌

데이터시트

SDS