Anti-Human CD183/CXCR3 Recombinant Antibody (1C6) (HW606307)

Name: Anti-Human CD183/CXCR3 Recombinant Antibody (1C6)
Brand: abinScience
SKU: HW606307
Price: 191 USD
Availability: InStock

가격(USD):

사양:

수량:

문의하기

개요

카탈로그 번호	HW606307
종 반응성	Human
응용 분야	FCM
숙주 종	Mouse
클론성	Monoclonal
이소타입	IgG2a, kappa
클론 ID	1C6
타겟	CXCR3, G protein-coupled receptor 9, CXC-R3, Interferon-inducible protein 10 receptor, IP-10 receptor, C-X-C chemokine receptor type 3, GPR9, CD183, CKR-L2, CXCR-3
내독소 수준	Please contact with the lab for this information.
순도	>95% as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	P49682
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4, 0.09% Sodium azide. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
배경	C-X-C chemokine receptor type 3 (CD183/CXCR3) is a ~40 kDa protein. Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of human mesangial cells (HMC) through a heterotrimeric G-protein signaling pathway. Binds to CCL21. Probably promotes cell chemotaxis response. Upon activation by PF4, induces activated T-lymphocytes migration mediated via downstream Ras/extracellular signal-regulated kinase (ERK) signaling. 1. Lasagni, L. et al. (2003) The Journal of experimental medicine 197, 1537-49. PMID: 12782716
참고사항	For research use only.