Anti-Human CD183/CXCR3 Recombinant Antibody (V3G6), PerCP (HW606147)

Name: Anti-Human CD183/CXCR3 Recombinant Antibody (V3G6), PerCP
Brand: abinScience
SKU: HW606147
Price: 268 USD
Availability: InStock

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개요
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참고 문헌
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개요

카탈로그 번호	HW606147
종 반응성	Human
응용 분야	FCM
숙주 종	Mouse
클론성	Monoclonal
이소타입	IgG1, kappa
클론 ID	V3G6
접합	PerCP
타겟	CXCR3, G protein-coupled receptor 9, CXC-R3, Interferon-inducible protein 10 receptor, IP-10 receptor, C-X-C chemokine receptor type 3, GPR9, CD183, CKR-L2, CXCR-3
내독소 수준	Please contact with the lab for this information.
관련 제품	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), PerCP
등록번호	P49682
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Store at 4°C for 12 months. Protect from light. Do not freeze.
배경	C-X-C chemokine receptor type 3 (CD183/CXCR3) is a ~40 kDa protein. Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of human mesangial cells (HMC) through a heterotrimeric G-protein signaling pathway. Binds to CCL21. Probably promotes cell chemotaxis response. Upon activation by PF4, induces activated T-lymphocytes migration mediated via downstream Ras/extracellular signal-regulated kinase (ERK) signaling. 1. Lasagni, L. et al. (2003) The Journal of experimental medicine 197, 1537-49. PMID: 12782716
참고사항	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.