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| 카탈로그 번호 | HC579107 |
|---|---|
| 종 반응성 | Human |
| 응용 분야 | ELISA, FCM, IHC, WB |
| 숙주 종 | Mouse |
| 클론성 | Monoclonal |
| 이소타입 | IgG1, kappa |
| 클론 ID | 47# |
| 타겟 | IL13R, IL-13RA2, IL-13 receptor subunit alpha-2, IL-13R-alpha-2, Interleukin-13-binding protein, CD213a2, IL-13R subunit alpha-2, IL13RA2, Interleukin-13 receptor subunit alpha-2 |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >95% as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | Q14627 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 배경 | Interleukin-13 receptor subunit alpha-2 (CD213a2/IL13RA2) is a ~44 kDa protein. Cell surface receptor that plays a role in the regulation of IL-13-mediated responses. Functions as a decoy receptor that inhibits IL-13- and IL-4-mediated signal transduction via the JAK-STAT pathway and thereby modulates immune responses and inflammation. Serves as a functional signaling receptor for IL-13 in an alternative pathway involving AP-1 ultimately leading to the production of TGFB1. 1. Rahaman, SO. et al. (2002) Cancer research 62, 1103-9. PMID: 11861389 2. Andrews, AL. et al. (2006) The Journal of allergy and clinical immunology 118, 858-65. PMID: 17030238 3. Fichtner-Feigl, S. et al. (2006) Nature medicine 12, 99-106. PMID: 16327802 |
| 참고사항 | For research use only. |
Flow-cytometry using anti-human CD213a2 antibody.A375 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD213a2 antibody monoclonal antibody (Catalog # HC579107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.
Western blot analysis was performed using anti-CD213a2/IL13RA2 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD213a2/IL13RA2 (Catalog No: HC579011)
Lane 2: negative control
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