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| 카탈로그 번호 | HY350147 |
|---|---|
| 종 반응성 | Human |
| 응용 분야 | ELISA, FCM |
| 숙주 종 | Mouse |
| 클론성 | Monoclonal |
| 이소타입 | IgG2a |
| 클론 ID | T-2 |
| 접합 | PerCP |
| 타겟 | Low affinity neurotrophin receptor p75NTR, TNFRSF16, CD271, Gp80-LNGFR, p75 ICD, Low-affinity nerve growth factor receptor, NGFR, NGF receptor, Tumor necrosis factor receptor superfamily member 16 |
| 내독소 수준 | Please contact with the lab for this information. |
| 관련 제품 | Mouse IgG2a Recombinant Isotype Control Antibody (C1.18.4), PerCP |
| 등록번호 | P08138 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 배경 | Tumor necrosis factor receptor superfamily member 16 (CD271/NGFR) is a ~45 kDa protein. Low affinity receptor which can bind to NGF, BDNF, NTF3, and NTF4. Forms a heterodimeric receptor with SORCS2 that binds the precursor forms of NGF, BDNF and NTF3 with high affinity, and has much lower affinity for mature NGF and BDNF. Plays an important role in differentiation and survival of specific neuronal populations during development. Can mediate cell survival as well as cell death of neural cells. Plays a role in the inactivation of RHOA. 1. Glerup, S. et al. (2014) Neuron 82, 1074-87. PMID: 24908487 2. Lin, Z. et al. (2015) eLife 4, e11692. PMID: 26646181 3. Baeza-Raja, B. et al. (2013) The Journal of neuroscience : the official journal of the Society for Neuroscience 33, 10221-34. PMID: 23785138 4. Li, H. et al. (2012) Science China. Life sciences 55, 367-74. PMID: 22566094 |
| 참고사항 | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |
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