Anti-Human BTLA/CD272 Recombinant Antibody (SAA0087), PE (HV375127)

Name: Anti-Human BTLA/CD272 Recombinant Antibody (SAA0087), PE
Brand: abinScience
SKU: HV375127
Price: 290 USD
Availability: InStock

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개요
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참고 문헌
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개요

카탈로그 번호	HV375127
종 반응성	Human
응용 분야	FCM
숙주 종	Human
클론성	Monoclonal
이소타입	IgG4, kappa
클론 ID	SAA0087
접합	PE
타겟	B- and T-lymphocyte attenuator, BTLA, CD272, B- and T-lymphocyte-associated protein
내독소 수준	Please contact with the lab for this information.
관련 제품	Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4), PE
등록번호	Q7Z6A9
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Store at 4°C for 12 months. Protect from light. Do not freeze.
배경	B- and T-lymphocyte attenuator (CD272/BTLA) is a ~32 kDa protein. Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14. In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells. _x005F_x000D_ _x005F_x000D_ 1. Watanabe, N. et al. (2003) Nature immunology 4, 670-9. PMID: 12796776 _x005F_x000D_ _x005F_x000D_ 2. Gavrieli, M. et al. (2003) Biochemical and biophysical research communications 312, 1236-43. PMID: 14652006 _x005F_x000D_ _x005F_x000D_ 3. Sedy, JR. et al. (2005) Nature immunology 6, 90-8. PMID: 15568026 _x005F_x000D_ _x005F_x000D_ 4. Cai, G. et al. (2008) Nature immunology 9, 176-85. PMID: 18193050 _x005F_x000D_ _x005F_x000D_ 5. Cheung, TC. et al. (2009) Journal of immunology (Baltimore, Md. : 1950) 183, 7286-96. PMID: 19915044
참고사항	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

이미지

Flow cytometry

Flow-cytometry PE using anti-human CD272 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an PE anti-human CD272 monoclonal antibody (Catalog HV375127) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

참고 문헌

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