

| 카탈로그 번호 | HV612014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human CD276 Polyclonal Antibody (HV612014) is a rabbit polyclonal antibody detecting CD276 in ELISA, IHC, WB. Suitable for Rattus norvegicus, Mus musculus, and Human.
Highlights
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| 종 반응성 | Human, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human CD276 (Thr47-Ser219). | ||||||||
| 테스트된 응용 분야 | WB | ||||||||
| 타겟 | 4Ig-B7-H3, B7 homolog 3, B7-H3, B7H3, CD276, CD276 antigen, Costimulatory molecule | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 순도 | >90% as determined by SDS-PAGE. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q5ZPR3 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 대체 이름 | CD276 antigen, 4Ig-B7-H3, B7 homolog 3, B7-H3, Costimulatory molecule, CD276, CD276, B7H3, PSEC0249, UNQ309/PRO352 | ||||||||
| 배경 | CD276 antigen is a ~57 kDa protein. May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. | ||||||||
| 참고사항 | For research use only. |

Western blot analysis was performed using anti-CD276 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Hela cell lysate
Lane 2: Lncap cell lysate
Lane 3: U2OS cell lysate
Lane 4: A431 cell lysate
Lane 5: HepG2 cell lysate
Lane 6: 293T cell lysate
Lane 7: MCF-7 cell lysate


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