Anti-Human CD307a/FCRL1 Polyclonal Antibody (HV653014)

Name: Anti-Human CD307a/FCRL1 Polyclonal Antibody
Brand: abinScience
SKU: HV653014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HV653014

설명

Anti-Human CD307a/FCRL1 Polyclonal Antibody (HV653014) is a rabbit polyclonal antibody detecting CD307a/FCRL1/IRTA5 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human CD307a/FCRL1 (Ala17-Asn293).

타겟

CD307a, Fc receptor homolog 1, hIFGP1, FcRL1, Fc receptor-like protein 1, FCRL1, IRTA5, IFGP family protein 1, FcR-like protein 1, FcRH1, Immune receptor translocation-associated protein 5, IFGP1, FCRH1

정제

Purified by antigen affinity column.

등록번호

Q96LA6

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

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제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Fc receptor-like protein 1 (CD307a/FCRL1) is a ~46 kDa protein. Type I transmembrane surface glycoprotein preferentially expressed by B-cells that regulates BCR-mediated signaling responses. Recruits ABL1 as the intracellular effector molecule to enhance B-cell activation. Also plays a negative role by suppressing ERK activation under homeostatic and BCR-stimulated conditions in a GRB2-dependent manner.

1. Leu, CM. et al. (2005) Blood 105, 1121-6. PMID: 15479727

참고사항

For research use only.

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