Anti-Human CD350/FZD10 Recombinant Antibody (ONC-005), APC (HV512137)

Name: Anti-Human CD350/FZD10 Recombinant Antibody (ONC-005), APC
Brand: abinScience
SKU: HV512137
Price: 290 USD
Availability: InStock

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개요
이미지
참고 문헌
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개요

카탈로그 번호	HV512137
종 반응성	Human
응용 분야	ELISA, FCM
숙주 종	Human
클론성	Monoclonal
이소타입	IgG1, kappa
클론 ID	ONC-005
접합	APC
타겟	FZD10, Fz-10, hFz10, Frizzled-10, CD350, FzE7
내독소 수준	Please contact with the lab for this information.
관련 제품	Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), APC
등록번호	Q9ULW2
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Store at 4°C for 12 months. Protect from light. Do not freeze.
배경	Frizzled-10 (CD350/FZD10) is a ~65 kDa protein. Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway. The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins.
참고사항	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

이미지

Flow cytometry

Flow-cytometry APC using anti-human CD350 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an APC anti-human CD350 monoclonal antibody (Catalog HV512137) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

참고 문헌

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