中文
English
한국어
日本語
Español
Français
Русский
| 카탈로그 번호 | HV512117 |
|---|---|
| 종 반응성 | Human |
| 응용 분야 | ELISA, FCM |
| 숙주 종 | Human |
| 클론성 | Monoclonal |
| 이소타입 | IgG1, kappa |
| 클론 ID | ONC-005 |
| 접합 | FITC |
| 타겟 | FZD10, Fz-10, hFz10, Frizzled-10, CD350, FzE7 |
| 내독소 수준 | Please contact with the lab for this information. |
| 관련 제품 | Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), FITC |
| 등록번호 | Q9ULW2 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 배경 | Frizzled-10 (CD350/FZD10) is a ~65 kDa protein. Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway. The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. |
| 참고사항 | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |
Flow-cytometry FITC using anti-human CD350 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an FITC anti-human CD350 monoclonal antibody (Catalog HV512117) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
