Anti-Human Frizzled-10 Recombinant Antibody (ONC-005) (HV512107)

Name: Anti-Human Frizzled-10 Recombinant Antibody (ONC-005)
Brand: abinScience
SKU: HV512107
Price: 191 USD
Availability: InStock

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개요

카탈로그 번호	HV512107
종 반응성	Human
응용 분야	ELISA, FCM, IHC, IP, RIA
숙주 종	Human
클론성	Monoclonal
이소타입	IgG1, kappa
클론 ID	ONC-005
타겟	FZD10, Fz-10, hFz10, Frizzled-10, CD350, FzE7
내독소 수준	Please contact with the lab for this information.
순도	>95% as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	Q9ULW2
형태	Liquid
저장 완충액	0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
배경	Frizzled-10 (CD350/FZD10) is a ~65 kDa protein. Receptor for Wnt proteins. Functions in the canonical Wnt/beta-catenin signaling pathway. The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins.
참고사항	For research use only.