Anti-Human Integrin alpha 2b/CD41 Recombinant Antibody (PT25) (HY355607)

Name: Anti-Human Integrin alpha 2b/CD41 Recombinant Antibody (PT25)
Brand: abinScience
SKU: HY355607
Price: 191 USD
Availability: InStock

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개요
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SDS

개요

카탈로그 번호	HY355607
종 반응성	Human
응용 분야	FCM
숙주 종	Mouse
클론성	Monoclonal
이소타입	IgG1, kappa
클론 ID	PT25
테스트된 응용 분야	FCM
타겟	CD41, ITGAB, GPIIb, ITGA2B, Platelet membrane glycoprotein IIb, GP2B, Integrin alpha-IIb, GPalpha IIb
내독소 수준	Please contact with the lab for this information.
순도	>95% as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	P08514
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4, 0.09% Sodium azide. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
배경	Integrin alpha-IIb (CD41/ITGA2B) is a ~113 kDa protein. Integrin alpha-IIb/beta-3 (ITGA2B:ITGB3) is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface. 1. Si-Tahar, M. et al. (1997) The Journal of biological chemistry 272, 11636-47. PMID: 9111081 2. Hermand, P. et al. (2003) The Journal of biological chemistry 278, 4892-8. PMID: 12477717
참고사항	For research use only.

이미지

Flow Cytometry

Flow-cytometry using anti-human CD41 antibody.Human peripheral blood monocytes were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD41 antibody monoclonal antibody (Catalog # HY355607 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.

참고 문헌

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Anti-Human Integrin alpha 2b/CD41 Recombinant Antibody (PT25).pdf

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Formula

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Anti-Human Integrin alpha 2b/CD41 Recombinant Antibody (PT25) (HY355607)

개요

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참고 문헌

데이터시트

SDS

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