Anti-Human CD45RO Recombinant Antibody (UCHL1), PE (HY195227)

Name: Anti-Human CD45RO Recombinant Antibody (UCHL1), PE
Brand: abinScience
SKU: HY195227
Price: 154 USD
Availability: InStock

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개요

카탈로그 번호	HY195227
종 반응성	Human
응용 분야	FCM
숙주 종	Mouse
클론성	Monoclonal
이소타입	IgG2a, kappa
클론 ID	UCHL1
접합	PE
타겟	T200, Leukocyte common antigen, CD45, L-CA, Receptor-type tyrosine-protein phosphatase C, PTPRC
내독소 수준	Please contact with the lab for this information.
관련 제품	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), PE
등록번호	P08575
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Store at 4°C for 12 months. Protect from light. Do not freeze.
배경	Receptor-type tyrosine-protein phosphatase C (CD45RO) is a ~147 kDa protein. Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. 1. Dunlock, VE. et al. (2022) Cell reports 39, 111006. PMID: 35767951
참고사항	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.