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Anti-Human Integrin alpha 3/CD49c Recombinant Antibody (84H7), FITC (HB114117)

Anti-Human Integrin alpha 3/CD49c Recombinant Antibody (84H7), FITC
Anti-Human Integrin alpha 3/CD49c Recombinant Antibody (84H7), FITC
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개요
카탈로그 번호HB114117
종 반응성Human
응용 분야ELISA, FCM, WB
숙주 종Mouse
클론성Monoclonal
이소타입IgG1, kappa
클론 ID84H7
접합FITC
타겟 ITGA3, CD49 antigen-like family member C, VLA-3 subunit alpha, GAPB3, CD49c, FRP-2, Integrin alpha-3, MSK18, Galactoprotein B3
내독소 수준 < 10 EU/mg
순도 >90% as determined by SDS-PAGE.
관련 제품 Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), FITC
등록번호 P26006
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

안정성 및 저장 Store at 4°C for 12 months. Protect from light. Do not freeze.
배경

Integrin alpha-3 (CD49c/ITGA3) is a ~116 kDa protein. Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.

참고사항 For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
이미지
  • Anti-Human Integrin alpha 3/CD49c Recombinant Antibody (84H7), FITC

    Flow CytoMetry

    Flow-cytometry using FITC anti-human CD49c antibody. Hela cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human CD49c monoclonal antibody (Catalog: HB114117, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

참고 문헌
Formula
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Volume
Molecular Weight *
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Formula
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Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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