Anti-Human CD49c/ITGA3 Recombinant Antibody (84H7) (HB114107)

Name: Anti-Human CD49c/ITGA3 Recombinant Antibody (84H7)
Brand: abinScience
SKU: HB114107
Price: 196 USD
Availability: InStock

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개요

카탈로그 번호	HB114107
종 반응성	Human
응용 분야	ELISA, FCM, IP, WB
숙주 종	Mouse
클론성	Monoclonal
이소타입	IgG1, kappa
클론 ID	84H7
타겟	ITGA3, CD49 antigen-like family member C, VLA-3 subunit alpha, GAPB3, CD49c, FRP-2, Integrin alpha-3, MSK18, Galactoprotein B3
내독소 수준	Please contact with the lab for this information.
순도	>95% as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	P26006
형태	Liquid
저장 완충액	0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
배경	Integrin alpha-3 (CD49c/ITGA3) is a ~116 kDa protein. Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
참고사항	For research use only.

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Flow Cytometry

Flow-cytometry using anti-human CD49c antibody.HeLa cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD49c antibody monoclonal antibody (Catalog # HB114107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.
Flow Cytometry

Flow-cytometry using anti-human CD49c antibody.KG-1 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD49c antibody monoclonal antibody (Catalog # HB114107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.
Flow Cytometry

Flow-cytometry using anti-human CD49c antibody.MG-63 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD49c antibody monoclonal antibody (Catalog # HB114107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.