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| 카탈로그 번호 | HY570015 |
|---|---|
| 설명 |
Anti-Human CD79α/CD79A Monoclonal Antibody (1A574) [1A574] (HY570015) is a mouse monoclonal antibody detecting CD79a in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 종 반응성 | Human |
| 응용 분야 | ELISA, IHC, WB |
| 숙주 종 | Mouse |
| 클론성 | Monoclonal |
| 이소타입 | IgG |
| 클론 ID | 1A574 |
| 면역원 | E. coli - derived recombinant human CD79α/CD79A (Met35-Gly219). |
| 타겟 | B-cell antigen receptor complex-associated protein alpha chain, Ig-alpha, MB-1 membrane glycoprotein, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein, CD79a, CD79A |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P11912 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 배경 | B-cell antigen receptor complex-associated protein alpha chain (CD79α/CD79A) is a ~25 kDa protein. Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. |
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human CD79α/CD79A Monoclonal Antibody (1A574)
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