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Anti-Human CD84/SLAMF5 Polyclonal Antibody (HV297024)

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개요
카탈로그 번호HV297024
설명
Anti-Human CD84 Polyclonal Antibody (HV297024) is a rabbit polyclonal antibody detecting CD84 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
종 반응성Human
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant Human CD84 (Lys22-Gly225).
타겟 Signaling lymphocytic activation molecule 5, Hly9-beta, Cell surface antigen MAX.3, Leukocyte differentiation antigen CD84, CD84, SLAM family member 5, SLAMF5
정제 Purified by antigen affinity column.
등록번호 Q9UIB8
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경

SLAM family member 5 (CD84) is a ~38 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Can mediate natural killer (NK) cell cytotoxicity dependent on SH2D1A and SH2D1B. Increases proliferative responses of activated T-cells and SH2D1A/SAP does not seem be required for this process.

1. Martin, M. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 3668-76. PMID: 11564780
2. Tangye, SG. et al. (2002) European journal of immunology 32, 1640-9. PMID: 12115647
3. Tangye, SG. et al. (2003) Journal of immunology (Baltimore, Md. : 1950) 171, 2485-95. PMID: 12928397
4. Zaiss, M. et al. (2003) Experimental hematology 31, 798-805. PMID: 12962726
5. Nanda, N. et al. (2005) Blood 106, 3028-34. PMID: 16037392
6. Álvarez-Errico, D. et al. (2011) Journal of immunology (Baltimore, Md. : 1950) 187, 5577-86. PMID: 22068234
7. Agod, Z. et al. (2018) Frontiers in immunology 9, 62. PMID: 29434592
참고사항 For research use only.
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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