Anti-Human LILRB2/CD85d/ILT4 Recombinant Antibody (J19.H1), FITC (HV255117)

Name: Anti-Human LILRB2/CD85d/ILT4 Recombinant Antibody (J19.H1), FITC
Brand: abinScience
SKU: HV255117
Price: 223 USD
Availability: InStock

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개요
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참고 문헌
데이터시트
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개요

카탈로그 번호	HV255117
종 반응성	Human
응용 분야	FCM
숙주 종	Mouse
클론성	Monoclonal
이소타입	IgG1, kappa
클론 ID	J19.H1
접합	FITC
타겟	CD85 antigen-like family member D, Monocyte/macrophage immunoglobulin-like receptor 10, MIR-10, ILT4, LIR-2, ILT-4, Immunoglobulin-like transcript 4, MIR10, CD85d, Leukocyte immunoglobulin-like receptor subfamily B member 2, Leukocyte immunoglobulin-like receptor 2, LIR2, LILRB2
내독소 수준	Please contact with the lab for this information.
관련 제품	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), FITC
등록번호	Q8N423
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Store at 4°C for 12 months. Protect from light. Do not freeze.
배경	Leukocyte immunoglobulin-like receptor subfamily B member 2 (CD85d/LILRB2) is a ~65 kDa protein. Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. Involved in the down-regulation of the immune response and the development of tolerance. Recognizes HLA-G in complex with B2M/beta-2 microglobulin and a nonamer self-peptide (peptide-bound HLA-G-B2M) triggering differentiation of type 1 regulatory T cells and myeloid-derived suppressor cells, both of which actively maintain maternal-fetal tolerance. Competes with CD8A for binding to class I MHC antigens. 1. Lepin, EJ. et al. (2000) European journal of immunology 30, 3552-61. PMID: 11169396 2. Shiroishi, M. et al. (2003) Proceedings of the National Academy of Sciences of the United States of America 100, 8856-61. PMID: 12853576 3. Shiroishi, M. et al. (2006) The Journal of biological chemistry 281, 10439-47. PMID: 16455647 4. Gregori, S. et al. (2010) Blood 116, 935-44. PMID: 20448110 5. Köstlin, N. et al. (2017) European journal of immunology 47, 374-384. PMID: 27859042 6. Chang, CC. et al. (2002) Nature immunology 3, 237-43. PMID: 11875462 8. Fanger, NA. et al. (1998) European journal of immunology 28, 3423-34. PMID: 9842885
참고사항	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.