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| 카탈로그 번호 | HC475013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | ELISA | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | SAA1580 | ||||
| 타겟 | APOER, LRP1, LRP-1, LRP-515, LRP-85, A2MR, Prolow-density lipoprotein receptor-related protein 1, Apolipoprotein E receptor, APR, CD91, LRPICD, Alpha-2-macroglobulin receptor | ||||
| 내독소 수준 | < 10 EU/mg | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | Q07954 | ||||
| RRID | Anti-Human CD91/LRP1 Antibody (SAA1580) (abinScience Cat# HC475013, RRID:AB_3727341) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Prolow-density lipoprotein receptor-related protein 1 (CD91/LRP1) is a ~504 kDa protein. Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. Acts as an LRPAP1 alpha-2-macroglobulin receptor. 1. May, P. et al. (2002) The Journal of biological chemistry 277, 18736-43. PMID: 11907044 2. May, P. et al. (2003) Traffic (Copenhagen, Denmark) 4, 291-301. PMID: 12713657 3. Kristensen, T. et al. (1990) FEBS letters 276, 151-5. PMID: 1702392 4. Klar, J. et al. (2015) Journal of medical genetics 52, 599-606. PMID: 26142438 5. Rauch, JN. et al. (2020) Nature 580, 381-385. PMID: 32296178 6. Kinoshita, A. et al. (2003) The Journal of biological chemistry 278, 41182-8. PMID: 12888553 7. Leal, SM. et al. (1997) The Journal of biological chemistry 272, 20572-6. PMID: 9252371 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human CD91/LRP1 Antibody (SAA1580)
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