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| 카탈로그 번호 | HF856014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human CELF2 (Lys41-Asp211). | ||||||||
| 타겟 | CELF-2, hNAPOR, Neuroblastoma apoptosis-related RNA-binding protein, CUGBP Elav-like family member 2, CUG-BP- and ETR-3-like factor 2, BRUNOL3, NAPOR, ETR3, CUGBP2, CUG triplet repeat RNA-binding protein 2, ETR-3, CELF2, ELAV-type RNA-binding protein 3, RNA-binding protein BRUNOL-3, Bruno-like protein 3, CUG-BP2 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O95319 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | CUGBP Elav-like family member 2 (CELF2) is a ~54 kDa protein. RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in embryonic, but not adult, skeletal muscle. Activates TNNT2 exon 5 inclusion by antagonizing the repressive effect of PTB. 1. Treiber, T. et al. (2017) Molecular cell 66, 270-284.e13. PMID: 28431233 | ||||||||
| 참고사항 | For research use only. |
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