Anti-Human CHCHD3 Polyclonal Antibody (HP686014)

Name: Anti-Human CHCHD3 Polyclonal Antibody
Brand: abinScience
SKU: HP686014
Price: 96 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HP686014

설명

Anti-Human CHCHD3 Polyclonal Antibody (HP686014) is a rabbit polyclonal antibody detecting CHCHD3 in ELISA, IHC, WB. Suitable for Human, Mouse, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human CHCHD3 (Ser58-Gly227).

타겟

MICOS complex subunit MIC19, Coiled-coil-helix-coiled-coil-helix domain-containing protein 3, MINOS3, MIC19, CHCHD3

정제

Purified by antigen affinity column.

등록번호

Q9NX63

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

MICOS complex subunit MIC19 (CHCHD3) is a ~26 kDa protein. Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology. Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription.

1. Ott, C. et al. (2015) PloS one 10, e0120213. PMID: 25781180

2. Stephan, T. et al. (2020) The EMBO journal 39, e104105. PMID: 32567732

3. Hu, C. et al. (2020) Cell death & disease 11, 940. PMID: 33130824

4. Liu, H. et al. (2012) PloS one 7, e34832. PMID: 22567091

참고사항

For research use only.

이미지

Western blot

Western blot analysis was performed using anti-CHCHD3 polyclonal antibody at 1μg/ml on various samples.
Lane 1: NIH3T3 cell lysate
Lane 2: Hela cell lysate
Lane 3: Jurkat cell lysate
Lane 4: Hepg2 cell lysate
Lane 5: A549 cell lysate
Lane 6: 293T cell lysate
Lane 7: Mouse kidney lysate
Lane 8: Mouse liver lysate
Lane 9: Mouse heart lysate
Lane 10: Rat kidney lysate
Lane11: Rat Liver lysate
Lane12: Rat heart lysate

참고 문헌

데이터시트

Anti-Human CHCHD3 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human CHCHD3 Polyclonal Antibody (HP686014)

개요

이미지

참고 문헌

데이터시트

SDS