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| 카탈로그 번호 | HC478013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | ELISA, IF, IP | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a | ||||
| 클론 ID | SAA0258 | ||||
| 타겟 | CHD-3, Mi2-alpha, ATP-dependent helicase CHD3, Mi-2 autoantigen 240 kDa protein, Chromodomain-helicase-DNA-binding protein 3, CHD3, hZFH, Zinc finger helicase | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | Q12873 | ||||
| RRID | Anti-Human CHD3 IP Antibody (SAA0258) (abinScience Cat# HC478013, RRID:AB_3729792) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | ATP-dependent chromatin remodeler CHD3 is a ~226 kDa protein. ATP-dependent chromatin-remodeling factor that binds and distorts nucleosomal DNA. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Involved in transcriptional repression as part of the NuRD complex. Required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindle organization and centrosome integrity. 1. Hoffmeister, H. et al. (2017) Nucleic acids research 45, 10534-10554. PMID: 28977666 2. Le Guezennec, X. et al. (2006) Molecular and cellular biology 26, 843-51. PMID: 16428440 3. Snijders Blok, L. et al. (2018) Nature communications 9, 4619. PMID: 30397230 4. Tong, JK. et al. (1998) Nature 395, 917-21. PMID: 9804427 5. Yamashita, D. et al. (2016) The Journal of biological chemistry 291, 11619-34. PMID: 27068747 6. Sillibourne, JE. et al. (2007) Molecular biology of the cell 18, 3667-80. PMID: 17626165 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human CHD3 IP Antibody (SAA0258)
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