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| 카탈로그 번호 | HP577014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human CHMP7 (Leu20-Gly226). | ||||||||
| 타겟 | Chromatin-modifying protein 7, Charged multivesicular body protein 7, CHMP7 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q8WUX9 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Charged multivesicular body protein 7 (CHMP7) is a ~50 kDa protein. ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope (NE) during late anaphase. Together with SPAST, the ESCRT-III complex promotes NE sealing and mitotic spindle disassembly during late anaphase. Recruited to the reforming NE during anaphase by LEMD2. Plays a role in the endosomal sorting pathway. 1. Vietri, M. et al. (2015) Nature 522, 231-5. PMID: 26040712 2. Gu, M. et al. (2017) Proceedings of the National Academy of Sciences of the United States of America 114, E2166-E2175. PMID: 28242692 3. Horii, M. et al. (2006) The Biochemical journal 400, 23-32. PMID: 16856878 | ||||||||
| 참고사항 | For research use only. |
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