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| 카탈로그 번호 | HT278014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human CHP2 Polyclonal Antibody (HT278014) is a rabbit polyclonal antibody detecting CHP2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human CHP2 (Asp13-Lys196). | ||||||||
| 타겟 | Calcineurin B homologous protein 2, Hepatocellular carcinoma-associated antigen 520, CHP2, HCA520 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O43745 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Calcineurin B homologous protein 2 (CHP2) is a ~22 kDa protein. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protecting cells from serum deprivation-induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus. | ||||||||
| 참고사항 | For research use only. |
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