Anti-Human CIB2 Polyclonal Antibody (HF922014)

Name: Anti-Human CIB2 Polyclonal Antibody
Brand: abinScience
SKU: HF922014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HF922014

설명

Anti-Human CIB2 Polyclonal Antibody (HF922014) is a rabbit polyclonal antibody detecting CIB2 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human CIB2 (Met1-Ile187).

타겟

Calcium and integrin-binding family member 2, Kinase-interacting protein 2, KIP 2, CIB2, KIP2

정제

Purified by antigen affinity column.

등록번호

O75838

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Calcium and integrin-binding family member 2 (CIB2) is a ~21 kDa protein. Calcium- and integrin-binding protein that plays a role in intracellular calcium homeostasis. Acts as an auxiliary subunit of the sensory mechanoelectrical transduction (MET) channel in hair cells. Essential for mechanoelectrical transduction (MET) currents in auditory hair cells and thereby required for hearing. Regulates the function of hair cell mechanotransduction by controlling the distribution of transmembrane channel-like proteins TMC1 and TMC2, and by regulating the function of the MET channels in hair cells. Required for the maintenance of auditory hair cell stereocilia bundle morphology and function and for hair-cell survival in the cochlea.

1. Riazuddin, S. et al. (2012) Nature genetics 44, 1265-71. PMID: 23023331

2. Seco, CZ. et al. (2016) European journal of human genetics : EJHG 24, 542-9. PMID: 26173970

3. Patel, K. et al. (2015) PloS one 10, e0133082. PMID: 26426422

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human CIB2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human CIB2 Polyclonal Antibody (HF922014)

개요

이미지

참고 문헌

데이터시트

SDS