

| 카탈로그 번호 | HT323014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human CIDEA Polyclonal Antibody (HT323014) is a rabbit polyclonal antibody detecting CIDEA in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human CIDEA (Arg35-Lys104). | ||||||||
| 타겟 | Cell death activator CIDE-A, CIDEA, Cell death-inducing DFFA-like effector A | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O60543 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Lipid transferase CIDEA is a ~24 kDa protein. Lipid transferase that promotes unilocular lipid droplet formation by mediating lipid droplet fusion. Lipid droplet fusion promotes their enlargement, restricting lipolysis and favoring lipid storage. Localizes on the lipid droplet surface, at focal contact sites between lipid droplets, and mediates atypical lipid droplet fusion by promoting directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair and occurs at a lower rate than that promoted by CIDEC. May also act as a CEBPB coactivator in epithelial cells to control the expression of a subset of CEBPB downstream target genes, including ID2, IGF1, PRLR, SOCS1, SOCS3, XDH, but not casein. 1. Liu, K. et al. (2009) American journal of physiology. Endocrinology and metabolism 297, E1395-413. PMID: 19843876 2. Abreu-Vieira, G. et al. (2015) Nature communications 6, 7433. PMID: 26118629 | ||||||||
| 참고사항 | For research use only. |
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