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| 카탈로그 번호 | HF544014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human COQ9 (Ser95-Arg318). | ||||||||
| 타겟 | Ubiquinone biosynthesis protein COQ9, mitochondrial, C16orf49, COQ9 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O75208 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Ubiquinone biosynthesis protein COQ9, mitochondrial is a ~35 kDa protein. Membrane-associated protein that warps the membrane surface to access and bind aromatic isoprenes with high specificity, including ubiquinone (CoQ) isoprene intermediates and presents them directly to COQ7, therefore facilitating the COQ7-mediated hydroxylase step. Participates in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. 1. Lohman, DC. et al. (2014) Proceedings of the National Academy of Sciences of the United States of America 111, E4697-705. PMID: 25339443 2. Lohman, DC. et al. (2019) Molecular cell 73, 763-774.e10. PMID: 30661980 3. Nicoll, CR. et al. (2024) Nature catalysis 7, 148-160. PMID: 38425362 | ||||||||
| 참고사항 | For research use only. |
Western blot analysis was performed using anti-COQ9 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse heart lysate
Lane 2: Rat heart lysate
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