Anti-Human CSNK2A1/CK2A1 Polyclonal Antibody (HX027014)

Name: Anti-Human CSNK2A1/CK2A1 Polyclonal Antibody
Brand: abinScience
SKU: HX027014
Price: 168 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD):

사양:

50ug
100ug

수량:

문의하기

개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HX027014

설명

Anti-Human CSNK2A1/CK2A1 Polyclonal Antibody (HX027014) is a rabbit polyclonal antibody detecting CSNK2A1 in ELISA, WB. Suitable for Mouse, Bovine, Chicken, Human, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human CSNK2A1/CK2A1 (Asp14-Ser337).

타겟

CSNK2A1, CK II alpha, CK2A1, Casein kinase II subunit alpha

정제

Purified by antigen affinity column.

등록번호

P68400, Q60737, Q8NEV1, P19139, P19784, O54833

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Casein kinase II subunit alpha (CSNK2A1/CK2A1) is a ~45 kDa protein. Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoint (SAC) that maintains cyclin-B-CDK1 activity and G2 arrest in response to spindle damage. Also required for p53/TP53-mediated apoptosis, phosphorylating 'Ser-392' of p53/TP53 following UV irradiation.

1. Keller, DM. et al. (2001) Molecular cell 7, 283-92. PMID: 11239457

2. Sayed, M. et al. (2001) Oncogene 20, 6994-7005. PMID: 11704824

3. Shin, S. et al. (2005) The EMBO journal 24, 3532-42. PMID: 16193064

4. Melander, F. et al. (2008) The Journal of cell biology 181, 213-26. PMID: 18411307

5. Chapman, JR. et al. (2008) EMBO reports 9, 795-801. PMID: 18583988

6. Wu, L. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 11200-5. PMID: 18678890

7. St-Denis, NA. et al. (2009) Molecular and cellular biology 29, 2068-81. PMID: 19188443

8. Takeishi, Y. et al. (2010) Genes to cells : devoted to molecular & cellular mechanisms 15, 761-71. PMID: 20545769

9. Hung, MS. et al. (2010) PloS one 5, e11418. PMID: 20625391

10. Matsumoto, G. et al. (2011) Molecular cell 44, 279-89. PMID: 22017874

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human CSNK2A1/CK2A1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human CSNK2A1/CK2A1 Polyclonal Antibody (HX027014)

개요

이미지

참고 문헌

데이터시트

SDS

빠른 접근

문의하기