Anti-Human CX3CR1 Recombinant Antibody (SAA1640) (HW331013)

Name: Anti-Human CX3CR1 Recombinant Antibody (SAA1640)
Brand: abinScience
SKU: HW331013
Price: 196 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD):

사양:

50ug
100ug
1mg

수량:

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HW331013

종 반응성

Human

응용 분야

ELISA, FCM

숙주 종

Mouse

클론성

Monoclonal

이소타입

IgG2a, kappa

클론 ID

SAA1640

타겟

CX3CR1, Beta chemokine receptor-like 1, Fractalkine receptor, CMK-BRL1, GPR13, CMKBRL1, CX3C chemokine receptor 1, V28, G-protein coupled receptor 13, C-X3-C CKR-1, CMK-BRL-1

내독소 수준

Please contact with the lab for this information.

순도

>95% as determined by SDS-PAGE.

정제

Protein A/G purified from cell culture supernatant.

등록번호

P49238

RRID

Anti-Human CX3CR1 Antibody (SAA1640) (abinScience Cat# HW331013, RRID:AB_3727401)

형태

Liquid

저장 완충액

0.01M PBS pH 7.4

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:2000-1:20000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

배경

CX3C chemokine receptor 1 (CX3CR1) is a ~40 kDa protein. Receptor for the C-X3-C chemokine fractalkine (CX3CL1) present on many early leukocyte cells; CX3CR1-CX3CL1 signaling exerts distinct functions in different tissue compartments, such as immune response, inflammation, cell adhesion and chemotaxis. CX3CR1-CX3CL1 signaling mediates cell migratory functions. Responsible for the recruitment of natural killer (NK) cells to inflamed tissues. Acts as a regulator of inflammation process leading to atherogenesis by mediating macrophage and monocyte recruitment to inflamed atherosclerotic plaques, promoting cell survival. Involved in airway inflammation by promoting interleukin 2-producing T helper (Th2) cell survival in inflamed lung.

1. Nishimura, M. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 168, 6173-80. PMID: 12055230

2. Fujita, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 5809-19. PMID: 23125415

3. Imai, T. et al. (1997) Cell 91, 521-30. PMID: 9390561

4. Fong, AM. et al. (1998) The Journal of experimental medicine 188, 1413-9. PMID: 9782118

5. Lucas, AD. et al. (2003) Circulation 108, 2498-504. PMID: 14581400

6. Landsman, L. et al. (2009) Blood 113, 963-72. PMID: 18971423

7. Leonardi, I. et al. (2018) Science (New York, N.Y.) 359, 232-236. PMID: 29326275

8. Nakayama, T. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 185, 6472-9. PMID: 20974991

참고사항

For research use only.

이미지

SDS-PAGE

SDS-PAGE for Anti-Human CX3CR1 Antibody (SAA1640)

참고 문헌

데이터시트

Anti-Human CX3CR1 Recombinant Antibody (SAA1640).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human CX3CR1 Recombinant Antibody (SAA1640) (HW331013)

개요

이미지

참고 문헌

데이터시트

SDS

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