Anti-Human CX3CR1 Recombinant Nanobody (11H11) (HW331023)

Name: Anti-Human CX3CR1 Recombinant Nanobody (11H11)
Brand: abinScience
SKU: HW331023
Price: 126 USD
Availability: InStock

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사양:

20ug
50ug
100ug
1mg

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HW331023

설명

Anti-Human CX3CR1 Nanobody (11H11) [11H11] (HW331023) is a alpaca monoclonal antibody detecting CX3CR1 in ELISA. Suitable for Human.

종 반응성

Human

응용 분야

ELISA

숙주 종

Alpaca

클론성

Monoclonal

이소타입

VHH-8His-Cys-tag

클론 ID

11H11

타겟

CX3CR1, Beta chemokine receptor-like 1, Fractalkine receptor, CMK-BRL1, GPR13, CMKBRL1, CX3C chemokine receptor 1, V28, G-protein coupled receptor 13, C-X3-C CKR-1, CMK-BRL-1

내독소 수준

Please contact with the lab for this information.

순도

>95% as determined by SDS-PAGE.

정제

Protein A/G purified from cell culture supernatant.

등록번호

P49238

형태

Liquid

저장 완충액

0.01M PBS pH 7.4

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:2000-1:20000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

CX3C chemokine receptor 1 (CX3CR1) is a ~40 kDa protein. Receptor for the C-X3-C chemokine fractalkine (CX3CL1) present on many early leukocyte cells; CX3CR1-CX3CL1 signaling exerts distinct functions in different tissue compartments, such as immune response, inflammation, cell adhesion and chemotaxis. CX3CR1-CX3CL1 signaling mediates cell migratory functions. Responsible for the recruitment of natural killer (NK) cells to inflamed tissues. Acts as a regulator of inflammation process leading to atherogenesis by mediating macrophage and monocyte recruitment to inflamed atherosclerotic plaques, promoting cell survival. Involved in airway inflammation by promoting interleukin 2-producing T helper (Th2) cell survival in inflamed lung.

1. Nishimura, M. et al. (2002) Journal of immunology (Baltimore, Md. : 1950) 168, 6173-80. PMID: 12055230

2. Fujita, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 5809-19. PMID: 23125415

3. Imai, T. et al. (1997) Cell 91, 521-30. PMID: 9390561

4. Fong, AM. et al. (1998) The Journal of experimental medicine 188, 1413-9. PMID: 9782118

5. Lucas, AD. et al. (2003) Circulation 108, 2498-504. PMID: 14581400

6. Landsman, L. et al. (2009) Blood 113, 963-72. PMID: 18971423

7. Leonardi, I. et al. (2018) Science (New York, N.Y.) 359, 232-236. PMID: 29326275

8. Nakayama, T. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 185, 6472-9. PMID: 20974991

참고사항

For research use only.

이미지

SDS-PAGE

SDS-PAGE for Anti-Human CX3CR1 Nanobody (11H11)

참고 문헌

데이터시트

Anti-Human CX3CR1 Recombinant Nanobody (11H11).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human CX3CR1 Recombinant Nanobody (11H11) (HW331023)

개요

이미지

참고 문헌

데이터시트

SDS

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