

| 카탈로그 번호 | HV254014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human D2HGDH Polyclonal Antibody (HV254014) is a rabbit polyclonal antibody detecting D2HGDH in ELISA, IHC, WB. Suitable for Rattus norvegicus, Mus musculus, and Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human D2HGDH (Arg56-Asp232). | ||||||||
| 타겟 | D2HGDH | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q8N465 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 대체 이름 | D-2-hydroxyglutarate dehydrogenase, mitochondrial, 1.1.99.39, D2HGDH, D2HGD | ||||||||
| 배경 | D-2-hydroxyglutarate dehydrogenase, mitochondrial (D2HGDH) is a ~56 kDa protein. Catalyzes the oxidation of D-2-hydroxyglutarate (D-2-HG) to alpha-ketoglutarate. Also catalyzes the oxidation of other D-2-hydroxyacids, such as D-malate (D-MAL) and D-lactate (D-LAC). Exhibits high activities towards D-2-HG and D-MAL but a very weak activity towards D-LAC. 1. Achouri, Y. et al. (2004) The Biochemical journal 381, 35-42. PMID: 15070399 2. Struys, EA. et al. (2005) American journal of human genetics 76, 358-60. PMID: 15609246 3. Struys, EA. et al. (2005) Annals of neurology 58, 626-30. PMID: 16037974 4. Kranendijk, M. et al. (2010) Human mutation 31, 279-83. PMID: 20020533 5. Yang, J. et al. (2021) Cell discovery 7, 3. PMID: 33431826 | ||||||||
| 참고사항 | For research use only. |

Western blot analysis was performed using anti-D2HGDH polyclonal antibody at 1ug/mL on various samples.
Lane 1: NIH3T3 cell lysate


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