

| 카탈로그 번호 | HB117014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human DCK Polyclonal Antibody (HB117014) is a rabbit polyclonal antibody detecting dCK in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human DCK (Met1-Leu260). | ||||||||
| 타겟 | dCK, Deoxyguanosine kinase, Deoxycytidine kinase, Deoxyadenosine kinase, DCK | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P27707 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Deoxycytidine kinase (DCK) is a ~30 kDa protein. Phosphorylates the deoxyribonucleosides deoxycytidine, deoxyguanosine and deoxyadenosine. Has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. It is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents. 1. Sabini, E. et al. (2003) Nature structural biology 10, 513-9. PMID: 12808445 2. Sabini, E. et al. (2008) Journal of molecular biology 378, 607-21. PMID: 18377927 3. Hazra, S. et al. (2009) Biochemistry 48, 1256-63. PMID: 19159229 4. Chottiner, EG. et al. (1991) Proceedings of the National Academy of Sciences of the United States of America 88, 1531-5. PMID: 1996353 5. Hazra, S. et al. (2010) Biochemistry 49, 6784-90. PMID: 20614893 6. Smal, C. et al. (2010) Archives of biochemistry and biophysics 502, 44-52. PMID: 20637175 | ||||||||
| 참고사항 | For research use only. |
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