Anti-Human DDX46 Polyclonal Antibody (HD537014)

Name: Anti-Human DDX46 Polyclonal Antibody
Brand: abinScience
SKU: HD537014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HD537014

설명

Anti-Human DDX46 Polyclonal Antibody (HD537014) is a rabbit polyclonal antibody detecting DDX46. Suitable for Rat, Human, and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human DDX46 (Asp322-Lys765).

타겟

DDX46, DEAD box protein 46, EC:3.6.4.13, KIAA0801, PRP5 homolog, Probable ATP-dependent RNA helicase DDX46

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

Q7L014

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Probable ATP-dependent RNA helicase DDX46 is a ~117 kDa protein. Component of the 17S U2 SnRNP complex of the spliceosome, a large ribonucleoprotein complex that removes introns from transcribed pre-mRNAs. The 17S U2 SnRNP complex (1) directly participates in early spliceosome assembly and (2) mediates recognition of the intron branch site during pre-mRNA splicing by promoting the selection of the pre-mRNA branch-site adenosine, the nucleophile for the first step of splicing. Within the 17S U2 SnRNP complex, DDX46 plays essential roles during assembly of pre-spliceosome and proofreading of the branch site.

1. Will, CL. et al. (2002) The EMBO journal 21, 4978-88. PMID: 12234937

2. Zhang, Z. et al. (2020) Nature 583, 310-313. PMID: 32494006

3. Tholen, J. et al. (2022) Science (New York, N.Y.) 375, 50-57. PMID: 34822310

4. Yang, F. et al. (2023) Nature communications 14, 897. PMID: 36797247

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-Human DDX46 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human DDX46 Polyclonal Antibody (HD537014)

개요

이미지

참고 문헌

데이터시트

SDS