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| 카탈로그 번호 | HA078013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | ELISA | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | SAA1871 | ||||
| 타겟 | DENN domain-containing protein 1A, Connecdenn, FAM31A, Protein FAM31A, KIAA1608, DENND1A, Connecdenn 1 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | Q8TEH3 | ||||
| RRID | Anti-Human DENND1A Antibody (SAA1871) (abinScience Cat# HA078013, RRID:AB_3727634) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | DENN domain-containing protein 1A (DENND1A) is a ~110 kDa protein. Guanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles and mediates exit from early endosomes. Binds phosphatidylinositol-phosphates (PtdInsPs), with some preference for PtdIns(3)P. 1. Marat, AL. et al. (2010) The Journal of biological chemistry 285, 10627-37. PMID: 20154091 2. Yoshimura, S. et al. (2010) The Journal of cell biology 191, 367-81. PMID: 20937701 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Human DENND1A Antibody (SAA1871)
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
