

| 카탈로그 번호 | HV696014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human DGKD Polyclonal Antibody (HV696014) is a rabbit polyclonal antibody detecting Human DGKD. Suitable for Mouse and Human.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human DGKD (Ser56-Asn314). | ||||||||
| 타겟 | DAG kinase eta, DGK-eta, DGKH, Diacylglycerol kinase eta, Diglyceride kinase eta, EC:2.7.1.107 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q86XP1 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 배경 | Diacylglycerol kinase eta (DGKD) is a ~134 kDa protein. Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (Probable). Plays a key role in promoting cell growth. Activates the Ras/B-Raf/C-Raf/MEK/ERK signaling pathway induced by EGF. Regulates the recruitment of RAF1 and BRAF from cytoplasm to membranes and their heterodimerization. 1. Murakami, T. et al. (2003) The Journal of biological chemistry 278, 34364-72. PMID: 12810723 2. Sato, M. et al. (2013) Pharmacology 92, 99-107. PMID: 23949095 3. Yasuda, S. et al. (2009) The Journal of biological chemistry 284, 29559-70. PMID: 19710016 | ||||||||
| 참고사항 | For research use only |
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