Anti-Human DIABLO Polyclonal Antibody (HP429014)

Name: Anti-Human DIABLO Polyclonal Antibody
Brand: abinScience
SKU: HP429014
Price: 168 USD
Availability: InStock

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HP429014

설명

Anti-Human DIABLO Polyclonal Antibody (HP429014) is a rabbit polyclonal antibody detecting DIABLO in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human DIABLO (His66-Asp239).

타겟

Second mitochondria-derived activator of caspase, Diablo homolog, mitochondrial, DIABLO, Smac, SMAC, Direct IAP-binding protein with low pI

정제

Purified by antigen affinity column.

등록번호

Q9NR28

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Diablo IAP-binding mitochondrial protein is a ~27 kDa protein. Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). Inhibits the activity of BIRC6/BRUCE by inhibiting its binding to caspases.

1. Bartke, T. et al. (2004) Molecular cell 14, 801-11. PMID: 15200957

2. Hunkeler, M. et al. (2023) Science (New York, N.Y.) 379, 1105-1111. PMID: 36758104

3. Ehrmann, JF. et al. (2023) Science (New York, N.Y.) 379, 1117-1123. PMID: 36758105

4. Dietz, L. et al. (2023) Science (New York, N.Y.) 379, 1112-1117. PMID: 36758106

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human DIABLO Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human DIABLO Polyclonal Antibody (HP429014)

개요

이미지

참고 문헌

데이터시트

SDS