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| 카탈로그 번호 | HV359014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human DKK4 Polyclonal Antibody (HV359014) is a rabbit polyclonal antibody detecting Dickkopf-related protein 4; Dickkopf-4; Dkk-4; hDkk-4; Dickkopf-related protein 4 short form; DKK4. Suitable for Human.
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human DKK4 (Gln107-His212). | ||||||||
| 타겟 | Dickkopf-related protein 4; Dickkopf-4; Dkk-4; hDkk-4; Dickkopf-related protein 4 short form; DKK4 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9UBT3 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 배경 | Dickkopf-related protein 4 (DKK4) is a ~24 kDa protein. Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. | ||||||||
| 참고사항 | For research use only |
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