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| 카탈로그 번호 | HP484013 | ||||
|---|---|---|---|---|---|
| 설명 |
Anti-Human DOT1L IP Recombinant Antibody (SAA0200) (HP484013) is a mouse monoclonal antibody detecting DOT1L in ELISA, IF, IP, IP-MS. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||
| 응용 분야 | ELISA, IF, IP, IP-MS | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | SAA0200 | ||||
| 타겟 | DOT1-like protein, Lysine N-methyltransferase 4, DOT1L, Histone-lysine N-methyltransferase, H3 lysine-79 specific, KMT4, H3-K79-HMTase, KIAA1814, Histone H3-K79 methyltransferase | ||||
| 내독소 수준 | < 10 EU/mg as determined by LAL method. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | Q8TEK3 | ||||
| RRID | Anti-Human DOT1L IP Antibody (SAA0200) (abinScience Cat# HP484013, RRID:AB_3729734) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Histone-lysine N-methyltransferase, H3 lysine-79 specific (DOT1L) is a ~164 kDa protein. Histone methyltransferase that methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA. 1. Feng, Q. et al. (2002) Current biology : CB 12, 1052-8. PMID: 12123582 2. Frisbie, VS. et al. (2024) Nature communications 15, 2467. PMID: 38503750 3. Singh, PR. et al. (2023) Nature communications 14, 8497. PMID: 38129415 4. Min, J. et al. (2003) Cell 112, 711-23. PMID: 12628190 | ||||
| 참고사항 | For research use only. | ||||
| Isotype Control | Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173) (MF533507) |
SDS-PAGE for Anti-Human DOT1L IP Antibody (SAA0200)
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