Anti-Human DYNLL1 Polyclonal Antibody (HX228014)

Name: Anti-Human DYNLL1 Polyclonal Antibody
Brand: abinScience
SKU: HX228014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HX228014

설명

Anti-Human DYNLL1 Polyclonal Antibody (HX228014) is a rabbit polyclonal antibody detecting DYNLL1 in ELISA, IHC, WB. Suitable for Bovine, Human, Macaca fascicularis, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human DYNLL1 (Cys2-Gly89).

타겟

DNCL1, Dynein light chain 1, cytoplasmic, DNCLC1, 8 kDa dynein light chain, DLC1, HDLC1, PIN, Dynein light chain LC8-type 1, DLC8, Protein inhibitor of neuronal nitric oxide synthase, DYNLL1

정제

Purified by antigen affinity column.

등록번호

P63167

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Dynein light chain 1, cytoplasmic (DYNLL1) is a ~10 kDa protein. Component of dynein, a family of motor proteins essential for movement along microtubules. Required for structural and functional integrity of cilia. Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.

1. Puthalakath, H. et al. (1999) Molecular cell 3, 287-96. PMID: 10198631

2. Vadlamudi, RK. et al. (2004) Cancer cell 5, 575-85. PMID: 15193260

3. Rayala, SK. et al. (2005) EMBO reports 6, 538-44. PMID: 15891768

4. Rayala, SK. et al. (2006) The Journal of biological chemistry 281, 19092-9. PMID: 16684779

5. He, YJ. et al. (2018) Nature 563, 522-526. PMID: 30464262

6. Swift, ML. et al. (2023) Nature structural & molecular biology 30, 1456-1467. PMID: 37696958

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human DYNLL1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human DYNLL1 Polyclonal Antibody (HX228014)

개요

이미지

참고 문헌

데이터시트

SDS

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