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| 카탈로그 번호 | HP048137 |
|---|---|
| 종 반응성 | Human |
| 응용 분야 | ELISA, FCM |
| 숙주 종 | Mouse |
| 클론성 | Monoclonal |
| 이소타입 | IgG2a, kappa |
| 클론 ID | SAA0771 |
| 접합 | APC |
| 타겟 | Ecto-ATP diphosphohydrolase 2, Ecto-ATPDase 2, ENTPD2, CD39 antigen-like 1, Ectonucleoside triphosphate diphosphohydrolase 2, NTPDase 2, Ecto-ATPase 2, CD39L1 |
| 내독소 수준 | Please contact with the lab for this information. |
| 관련 제품 | Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), APC |
| 등록번호 | Q9Y5L3 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 배경 | Ectonucleoside triphosphate diphosphohydrolase 2 (ENTPD2/CD39L1) is a ~53 kDa protein. Catalyzes the hydrolysis of nucleoside triphosphates (NTPs) and diphosphates (NDPs), with a marked preference for triphosphonucleosides over diphosphonucleosides. The enzyme sequentially removes phosphate groups in two successive steps, converting NTPs to nucleoside monophosphates (NMPs) via NDP intermediates. This activity contributes to the regulation of extracellular nucleotides levels. ATP hydrolysis is characterized by fast ADP accumulation and delayed AMP formation, reflecting limited ADP hydrolase activity. Hydrolyzes ADP and UDP only to a marginal extent, and does not hydrolyze AMP. 1. Mateo, J. et al. (1999) British journal of pharmacology 128, 396-402. PMID: 10510450 2. Mateo, J. et al. (2003) The Journal of biological chemistry 278, 39960-8. PMID: 12888562 3. Mukasa, T. et al. (2005) Biochemistry 44, 11160-70. PMID: 16101300 4. Kukulski, F. et al. (2005) Purinergic signalling 1, 193-204. PMID: 18404504 |
| 참고사항 | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |
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