Anti-Human EphA2 Recombinant Antibody (SAA0832) (HB738107)

Name: Anti-Human EphA2 Recombinant Antibody (SAA0832)
Brand: abinScience
SKU: HB738107
Price: 191 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호	HB738107
종 반응성	Human, Mouse
응용 분야	ELISA, FCM, FuncS, IF, WB, IHC
숙주 종	Mouse
클론성	Monoclonal
이소타입	IgG2a
클론 ID	SAA0832
타겟	Epithelial cell kinase, Tyrosine-protein kinase receptor ECK, EPHA2, Ephrin type-A receptor 2, ECK
내독소 수준	Please contact with the lab for this information.
순도	>95% as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	P29317
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4, 0.09% Sodium azide. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
배경	Ephrin type-A receptor 2 (EPHA2) is a ~108 kDa protein. Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway. May also participate in UV radiation-induced apoptosis and have a ligand-independent stimulatory effect on chemotactic cell migration.
참고사항	For research use only.

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Flow Cytometry

Flow-cytometry using anti-human EPHA2 antibody.A431 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human EPHA2 antibody monoclonal antibody (Catalog # HB738107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.

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