

| 카탈로그 번호 | HB152137 |
|---|---|
| 종 반응성 | Human |
| 응용 분야 | FCM |
| 숙주 종 | Mouse |
| 클론성 | Monoclonal |
| 이소타입 | IgG1, kappa |
| 클론 ID | ABT-007 |
| 접합 | APC |
| 타겟 | EPOR, Erythropoietin receptor, EPO-R |
| 내독소 수준 | Please contact with the lab for this information. |
| 관련 제품 | Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC |
| 등록번호 | P19235 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 배경 | Erythropoietin receptor (EPOR) is a ~55 kDa protein. Receptor for erythropoietin, which mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. 1. Zhan, H. et al. (1999) Protein engineering 12, 505-13. PMID: 10388848 2. Winkelmann, JC. et al. (1990) Blood 76, 24-30. PMID: 2163695 3. Jones, SS. et al. (1990) Blood 76, 31-5. PMID: 2163696 4. Middleton, SA. et al. (1996) The Journal of biological chemistry 271, 14045-54. PMID: 8662939 5. Syed, RS. et al. (1998) Nature 395, 511-6. PMID: 9774108 6. Kirito, K. et al. (2002) Blood 99, 102-10. PMID: 11756159 |
| 참고사항 | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |
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