Anti-Human ERLIN1 Polyclonal Antibody (HF518014)

Name: Anti-Human ERLIN1 Polyclonal Antibody
Brand: abinScience
SKU: HF518014
Price: 168 USD
Availability: InStock

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100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HF518014

설명

Anti-Human ERLIN1 Polyclonal Antibody (HF518014) is a rabbit polyclonal antibody detecting ERLIN1 in ELISA, IHC, WB. Suitable for Human, Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human ERLIN1 (Glu29-Thr173).

타겟

SPFH1, SPFH domain-containing protein 1, Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1, C10orf69, KEO4, Protein KE04, Endoplasmic reticulum lipid raft-associated protein 1, ERLIN1, Erlin-1, KE04

정제

Purified by antigen affinity column.

등록번호

O75477

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Erlin-1 (ERLIN1) is a ~39 kDa protein. Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex.

1. Teo, QW. et al. (2023) Developmental cell 58, 2495-2509.e6. PMID: 37683630

2. Huber, MD. et al. (2013) The Journal of cell biology 203, 427-36. PMID: 24217618

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Human ERLIN1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human ERLIN1 Polyclonal Antibody (HF518014)

개요

이미지

참고 문헌

데이터시트

SDS